Review article: Coagulation cascade and therapeutics update

coagulation cascade  The coagulation process is characterised by a cascade of events which lead to the formation of a blood clot Proteins called clotting factors initiate reactions The coagulation cascade can be divided into initiation and amplification phases After vessel injury the TF:FVIIa complex activates both FX and

The concept of a coagulation cascade describes the biochemical interactions of the coagulation factors, but has flaws as a model of the hemostatic process  You can remember the factors in the common pathway by remembering the bills in your wallet smaller than a $20 Don't forget the $2 bill !! Coagulation made easy

The coagulation cascade test is conducted to diagnose bleeding disorders such as haemophilia and liver diseases The analysis is also conducted Antithrombin activity inhibits many clotting factors in the coagulation cascade Learn more about how antithrombin impact the coagulation cascade